Will freezer burnt meatloaf make you sick?

No, freezer-burnt meatloaf will not make you sick. Freezer burn is a result of dehydration and oxidation of food caused by prolonged storage in a freezer. It can make food unappealing in appearance and taste, but it does not pose any health risks. The meatloaf may have a loss of flavour, texture and nutrients, but it is still safe to eat.