Were tomatoes considered poisonous when they were discovered by Europeans?

Tomatoes were not considered poisonous when they were discovered by Europeans. The misconception regarding the perceived toxicity of tomatoes likely arose due to confusion with two unrelated plant species that contain toxic substances: deadly nightshade (Atropa belladonna) and bittersweet nightshade (Solanum dulcamara). These plants belong to the same family as tomatoes (Solanaceae), but tomatoes themselves are not poisonous.