Is a chicken casserole with sour creme in it that was left out all night safe to eat?

It is not safe to eat a chicken casserole with sour cream that was left out overnight. Sour cream is a dairy product that can spoil quickly at room temperature.

According to the USDA, perishable foods, including dairy products, should not be left out for more than two hours at room temperature. After that, they should be discarded. Leaving sour cream out overnight gives the bacteria enough time to grow to harmful levels, potentially causing foodborne illness if consumed.

To ensure food safety, it is important to follow proper storage and handling practices. Always refrigerate perishable foods promptly and keep them at a consistent temperature of 40°F (4°C) or below. If in doubt, it is better to discard any food that has been left out for an extended period of time to avoid potential health risks.