Regular heavy drinkers usually have to drink more and in order the same effect?

That's correct. Regular heavy drinkers often develop tolerance, meaning they need to drink more alcohol to achieve the same effect they used to get with smaller amounts. This is a sign of alcohol dependence and is a serious issue.

Here's why tolerance develops:

* Body adapts: The body adjusts to the presence of alcohol, becoming more efficient at processing it. This means that the same amount of alcohol has less of an impact, leading to the need for more to feel the desired effects.

* Changes in brain chemistry: Alcohol affects neurotransmitters in the brain, and chronic alcohol use can lead to changes in these pathways. This can make the brain less sensitive to alcohol, requiring more to achieve the same level of stimulation or relaxation.

It's important to remember that tolerance is a sign of potential problems, not a sign of strength. If you or someone you know is experiencing alcohol dependence, it's crucial to seek professional help.