If you drank a fifth of 40 proof vodka how long will it stay in your system?

It typically takes around 1 - 2 hours to metabolize 1 drink (14 grams of pure alcohol). A fifth (750ml) of 40 proof vodka is equivalent to 17.5 drinks, so it could take around 17.5 - 35 hours for your body to metabolize all of the alcohol in your system. However, numerous factors, such as age, weight, gender, liver health, and metabolism can affect how long alcohol remains in the system.