Is it ok to eat spaghetti sauce that has been sitting out overnight if reheated over 180 degrees F?

It's generally not recommended to eat spaghetti sauce that has been sitting out overnight, even if reheated to over 180 degrees Fahrenheit. Here's why:

* Bacteria Growth: Bacteria can multiply rapidly at room temperature. While reheating to a high temperature can kill most bacteria, it doesn't necessarily destroy all toxins they may have produced.

* Food Safety Guidelines: The USDA recommends that perishable foods, including spaghetti sauce, be refrigerated within two hours of being cooked. Leaving it out overnight significantly increases the risk of foodborne illness.

Even if it looks and smells fine, it's better to err on the side of caution and throw it out.

Here's a safer alternative:

* Refrigerate the sauce within two hours of cooking: This prevents bacterial growth.

* Reheat it thoroughly to a rolling boil for at least 1 minute: This ensures the sauce reaches a temperature hot enough to kill any potential bacteria.

Enjoy your delicious spaghetti sauce safely!